Sony MDR-7506 is still my preferred set of cans for basically everything. They have impeccable balance and are extremely easy to maintain and repair. ATH-M50 is good for when I want a more isolated experience, but they definitely don't have the same overall audio quality as the Sony pair.
When I'm at home and using open air, the Grado SR-80 is a great set. Their soundscape is amazingly well done.